By M. Benkö, B. Harrach (auth.), Prof.Dr. Walter Doerfler, Petra Böhm (eds.)
After 3 volumes on adenoviruses in 1995 the earlier years have obvious speedy growth within the box of adenovirus examine. furthermore, adenoviruses have attracted massive curiosity as vectors in gene move regimens.
Read Online or Download Adenoviruses: Model and Vectors in Virus-Host Interactions: Virion-Structure, Viral Replication and Host-Cell Interactions PDF
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Extra info for Adenoviruses: Model and Vectors in Virus-Host Interactions: Virion-Structure, Viral Replication and Host-Cell Interactions
We hope that the presentation of the above data will increase awareness about the incredible heterogeneity of adenoviruses. This might stimulate further work on other subjects than HAdV-2 or 5, which would ultimately contribute to the recognition of new mechanisms used by the less sophisticated adenoviruses in their replication strategies. With the comparative analyses of distantly related viruses, the functional and structural studies will also be better fuelled. For confirmation of the provisional adenovirus species classification, many different strains are being examined, and these studies will contribute further to the clarification of the unanswered questions.
Adenoviridae. In: Tidona CA, Darai G (eds) The Springer index of viruses. Springer-Verlag, Berlin, Heidelberg, New York, pp 29-33 DAVISON AJ, TELFORD EAR, WATSON MS, McBRIDE K, MAUTNER V (1993) The DNA sequence of adenovirus type 40. J Mol BioI 234:1308-1316 DAVISON AJ, WRIGHT KM, HARRACH B (2000) DNA sequence of frog adenovirus. J Gen Viro181:2431-2439 ESFORD LE, HAJ-AHMAD Y (1994) Sequence analysis of the putative E3 region of bovine adenovirus type 2. Intervirology 37:277-286 ESSBAUER S, AHNE W (2001) Viruses of lower vertebrates.
3). terminus of E6AP (E6AP is the human papillomavirus 16 E6 oncoprotein-associated protein), which contains a conserved catalytic cysteine residue indispensable to the formation of a thiol ester bond with a ubiquitin moiety (STAUB et al. 1996). In addition, the ubiquitin-protein ligases quite often contain the calcium/lipid binding membrane localization domain C2, as in the first ubiquitin-protein ligase described, Nedd4 (KUMAR et al. 1997). Domains of E3 enzymes provide a flexible means of linking a conserved ubiquitination function to potentially very numerous substrates in eukaryotic cells.
Adenoviruses: Model and Vectors in Virus-Host Interactions: Virion-Structure, Viral Replication and Host-Cell Interactions by M. Benkö, B. Harrach (auth.), Prof.Dr. Walter Doerfler, Petra Böhm (eds.)