By Eugénie Bergogne-Bérézin (auth.), Mauro Bendinelli, Herman Friedman, Eugénie Bergogne-Bérézin (eds.)
There is at present expanding curiosity about the biology and illness because of Acinetobacter species. Such curiosity, in spite of the fact that, built quite slowly as a result of necessity to explain the complicated taxonomy of those organisms. a lot paintings used to be had to establish a number of species as individuals of this genus, to acknowledge their epidemiologic profile, their pathogenic function and their expanding significance as multi-antibiotic resistant organisms. in recent times development of genetic techniques, popularity of plasmids, integrons and chromosomal assets of resistance mechanisms aroused curiosity at the function of Acinetobacters in ailment by means of many microbiologists and clinicians, particularly internists and infectious sickness experts. during this regard, physicians are often faced with super tough healing ways for remedy and prevention of critical nosocomial infections because of multi antibiotic resistant Acinetobacter. in addition, fresh observations of group obtained infections were said, particularly in sufferers with a variety of chance elements equivalent to immuno-deficiencies. additionally, it's now changing into glaring that Acinetobacter infections happen often in violent occasions similar to earthquake or battle zones.
The mechanisms of Acinetobacter virulence have gotten more and more transparent, delivering new insights into their pathogenic position in group got infections. it's obvious the time is acceptable for specified assessment of the expanding wisdom referring to very important new info, either scientific and healing, in particular details relating virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are collecting in virtually an exponential demeanour due to the fact e-book of prior books in this topic in 1991 and 1996.
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Extra resources for Acinetobacter Biology and Pathogenesis
In one of the few studies performed for validation of this identification system, Gerner-Smidt et al. used a set of 198 Acinetobacter strains that had been identified previously by DNA-DNA hybridization. They showed that the genetically closely related and clinically most relevant species A. baumannii and Acinetobacter genomic species 13TU cannot be distinguished, while A. , 1991). This observation led to the proposal to lump these species together in the so-called A. calcocaceticus – A. , 1991).
2001). These interesting findings warrant further investigations. In particular, it has to be demonstrated that it is not humans handling vegetables that are the source of Acinetobacter genomic species 3 on vegetables. , found acinetobacters in 22 of 60 soil samples in Hong Kong, and the most frequent species were Acinetobacter genomic species 3 (27%) and A. baumannii (23%); only one sample yielded A. , 2001). In an unpublished study from Germany, 92 of 163 samples (56%) from soil and surface water yielded acinetobacters, and A.
Recently, some intraspecific similarities for strains of five species and two tentative novel species have been published (Vaneechoutte and De Baere, 2008). 6% are indicative that two strains belong to different species. These findings indicate that the 16S rDNA sequence molecule may not be sufficient for identification of all Acinetobacter species. , 1998). , 2005). 92. Overview of the Microbial Characteristics, Taxonomy, and Epidemiology 31 The resolving capacity of the phylogenetic analysis of protein-encoding genes is thought to be greater than that of the 16S rRNA sequence (Ochman and Wilson, 1987).
Acinetobacter Biology and Pathogenesis by Eugénie Bergogne-Bérézin (auth.), Mauro Bendinelli, Herman Friedman, Eugénie Bergogne-Bérézin (eds.)